General Information

  • ID:  hor004307
  • Uniprot ID:  A0A8J5MMN2
  • Protein name:  Tachykinin
  • Gene name:  NA
  • Organism:  Homarus americanus (American lobster)
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SGFLGMR
  • Length:  7
  • Propeptide:  MVRACTWAVLLGVVVVMGVVSAAGEGQDTPQDRERRAPSGFLGMRGKKDASTALDDNTAASEYSSLPDPYPLYGLRDNNLPMLFAVPWKTKKAPSGFLGMRGKKSDEEVFSDATADNDLEILLKRAPSGFLGMRGKKAPSGFLGMRGKKAPSGFLGMRGKKYYDDDSDMDAYIQALTAVVDGQQQQKRAPSGFLGMRGKKAYYSENPDEEISMTGVDKRTPSGFLGVRCSLHSALPCLKIIPRAVIPA
  • Signal peptide:  MVRACTWAVLLGVVVVMGVVSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004307_AF2.pdbhor004307_ESM.pdb

Physical Information

Mass: 87411 Formula: C33H54N10O9S
Absent amino acids: ACDEHIKNPQTVWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: 34.29 Boman Index: -619
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 55.71
Instability Index: -220 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18304551
  • Title:  Mass Spectral Characterization of Peptide Transmitters/Hormones in the Nervous System and Neuroendocrine Organs of the American Lobster Homarus Americanus